Ryuichi Tozawa Selected Research

1- ((1- (3- acetoxy- 2,2- dimethylpropyl)- 7- chloro- 5- (2,3- dimethoxyphenyl)- 2- oxo- 1,2,3,5- tetrahydro- 4,1- benzoxazepin- 3- yl)acetyl)piperidine- 4- acetic acid

8/2007	Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs.
12/2003	Comparing myotoxic effects of squalene synthase inhibitor, T-91485, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in human myocytes.
7/2003	Lipid-lowering properties of TAK-475, a squalene synthase inhibitor, in vivo and in vitro.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Ryuichi Tozawa Research Topics

Disease

5	Dyslipidemias (Dyslipidemia) 02/2018 - 07/2003
4	NGLY1 deficiency 01/2021 - 01/2020
3	Atherosclerosis 01/2017 - 04/2005
2	Intellectual Disability (Idiocy) 01/2021 - 01/2020
2	Alacrima 01/2021 - 01/2020
2	Muscular Diseases (Myopathy) 10/2019 - 08/2007
2	Hyperlipidemias (Hyperlipidemia) 01/2018 - 02/2012
2	Alcoholic Fatty Liver 01/2018 - 05/2017
2	Fibrosis (Cirrhosis) 05/2017 - 01/2017
2	Neoplasms (Cancer) 01/2017 - 02/2013
2	Alzheimer Disease (Alzheimer's Disease) 04/2014 - 07/2011
2	Myotoxicity 08/2007 - 12/2003
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2021
1	Movement Disorders (Movement Disorder) 01/2020
1	Dysferlinopathy 10/2019
1	Obesity 01/2018
1	Hepatocellular Carcinoma (Hepatoma) 01/2018
1	Inflammation (Inflammations) 01/2018
1	Liver Cirrhosis (Hepatic Cirrhosis) 05/2017
1	Aortic Dissection 01/2017
1	Aortic Aneurysm (Aneurysm, Aortic) 01/2017
1	Cachexia 01/2017
1	Hyperplasia 01/2017
1	Thrombosis (Thrombus) 01/2017
1	Body Weight (Weight, Body) 01/2016
1	Liver Diseases (Liver Disease) 05/2015
1	Hepatomegaly 05/2015
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2014
1	Breast Neoplasms (Breast Cancer) 02/2013
1	Hypercholesterolemia 02/2012
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 02/2012
1	Cognitive Dysfunction 07/2011
1	Coronary Artery Disease (Coronary Atherosclerosis) 08/2007
1	Rhabdomyosarcoma 12/2003

Drug/Important Bio-Agent (IBA)

5	LipidsIBA 02/2018 - 12/2003
3	Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine AmidaseIBA 01/2021 - 01/2020
3	CholesterolIBA 01/2017 - 08/2007
3	1- ((1- (3- acetoxy- 2,2- dimethylpropyl)- 7- chloro- 5- (2,3- dimethoxyphenyl)- 2- oxo- 1,2,3,5- tetrahydro- 4,1- benzoxazepin- 3- yl)acetyl)piperidine- 4- acetic acidIBA 08/2007 - 07/2003
2	DysferlinIBA 10/2019 - 10/2019
2	Pharmaceutical PreparationsIBA 10/2019 - 04/2005
2	LDL Receptors (LDL Receptor)IBA 05/2017 - 02/2012
2	Testosterone (Sustanon)FDA Link 01/2017 - 04/2014
2	Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)IBA 05/2015 - 08/2007
2	ApolipoproteinsIBA 01/2015 - 04/2005
2	Mevalonic Acid (Mevalonate)IBA 08/2007 - 12/2003
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 08/2007 - 12/2003
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	N-acetylglucosaminylasparagineIBA 01/2021
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021
1	Bile Acids and Salts (Bile Acids)IBA 02/2018
1	neuromedin UIBA 01/2018
1	Ezetimibe (Zetia)FDA Link 01/2018
1	Cholestyramine Resin (Questran)FDA LinkGeneric 01/2018
1	torcetrapibIBA 01/2018
1	NeuropeptidesIBA 01/2018
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2018
1	Angiotensin II Type 1 Receptor BlockersIBA 05/2017
1	candesartan cilexetil (Amias)FDA Link 05/2017
1	Triglycerides (Triacylglycerol)IBA 05/2017
1	Choline (Choline Chloride)IBA 05/2017
1	Pioglitazone (Actos)FDA Link 05/2017
1	Interleukin-6 (Interleukin 6)IBA 05/2017
1	2,4-thiazolidinedione (thiazolidinedione)IBA 05/2017
1	Alanine Transaminase (SGPT)IBA 05/2017
1	Amino Acids FDA Link 05/2017
1	CollagenIBA 01/2017
1	Anabolic AgentsIBA 01/2017
1	Insulin (Novolin)FDA Link 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2016
1	Blood Glucose (Blood Sugar)IBA 01/2016
1	FarnesolIBA 05/2015
1	Apolipoproteins B (ApoB)IBA 01/2015
1	Atorvastatin (Lipitor)FDA Link 07/2014
1	HDL CholesterolIBA 06/2014
1	T-3256336IBA 02/2013
1	CaspasesIBA 02/2013
1	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 02/2012
1	LigandsIBA 02/2012
1	Amyloid (Amyloid Fibrils)IBA 07/2011
1	TAK-085IBA 07/2011
1	Peptides (Polypeptides)IBA 07/2011
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 07/2011
1	Terpenes (Terpenoids)IBA 08/2007
1	LDL CholesterolIBA 08/2007
1	Creatine Kinase (Creatine Phosphokinase)IBA 08/2007
1	Acetates (Acetic Acid Esters)FDA Link 08/2007
1	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 08/2007
1	cerivastatin (Kazak)FDA Link 08/2007
1	mevalonolactoneIBA 08/2007
1	Lysophospholipase (Phospholipase B)IBA 04/2005
1	EnzymesIBA 04/2005
1	Coenzyme A (CoA)IBA 12/2003
1	SqualeneIBA 12/2003

Therapy/Procedure

2	Therapeutics 07/2014 - 12/2003